Selected Publications 

Álvarez-Castro JM 2020 Gene-environment interaction in the era of precision medicine - filling the potholes rather than starting to build a new road. Frontiers in Genetics 11:921

Álvarez-Castro JM and RM Crujeiras 2019 Orthogonal decomposition of the genetic variance for epistatic traits under linkage disequilibrium - Applications to the analysis of Bateson-Dobzhansky-Müller incompatibilities and sign epistasis. Frontiers in Genetics 10:54

Le Rouzic A and JM Álvarez-Castro 2016 Epistasis-induced evolutionary plateaus in selection responses. The American Naturalist 188(6):E134-E150

Álvarez-Castro JM 2016 Genetic architecture. In Encyclopedia of Evolutionary Biology, RM Kliman (Ed), Vol 2 pp127-135 Oxford: Academic Press

Álvarez-Castro JM, R-C Yang (Eds) 2015 Models and Estimation of Genetic Effects. Frontiers Media SA, Lausanne

Álvarez-Castro JM and A Le Rouzic 2015 On the partitioning of genetic variance with epistasis. In Epistasis: Methods and Protocols, JH Moore and SM Williams (Eds), Methods in Molecular Biology Series, Vol 1253 pp95-114, Humana Press-Springer, New York

Álvarez-Castro JM 2014 Dissecting genetic effects with imprinting. Frontiers in Ecology and Evolution 2:51

Schneider K, C Fuchs, A Dobay, A Rottach, W Qin, P Wolf, JM Álvarez-Castro, MM Nalaskowski, E Kremmer, V Schmid, H Leonhardt and L Schermelleh 2013 Dissection of cell cycle–dependent dynamics of Dnmt1 by FRAP and diffusion-coupled modeling. Nucleic Acids Research 41:4860-76

Álvarez-Castro JM, Ö Carlborg and L Rönnegård 2012 Estimation and interpretation of genetic effects with epistasis using the NOIA model. In Quantitative Trait Loci (QTL): Methods and Protocols, SA Rifkin (Ed), Methods in Molecular Biology Series, Vol 871 pp191-204, Humana Press-Springer, New York

Álvarez-Castro JM, R-C Yang 2011 Multiallelic models of genetic effects and variance decomposition in non-equilibrium populations. Genetica 139:1119-1134

Svetec N, A Werzner, R Wilches, P Pavlidis, JM Álvarez-Castro, KW Broman, D Metzler and W Stephan 2011 Identification of X-linked quantitative trait loci affecting cold tolerance in Drosophila melanogaster and fine mapping by selective sweep analysis. Molecular Ecology 20:530-544

Álvarez-Castro JM, A Le Rouzic and Ö Carlborg 2008 How to perform meaningful estimates of genetic effects. PLoS Genetics 4(5):e1000062

Álvarez-Castro JM and Ö Carlborg 2007 A unified model for functional and statistical epistasis and its application in quantitative trait loci analysis. Genetics 176:1151–1167

Álvarez-Castro JM and G Alvarez 2005 Models of general frequency-dependent selection and mating-interaction effects and the analysis of selection patterns in Drosophila inversion polymorphisms. Genetics 170:1167-1179