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Páxinas persoais  »  Eduardo Marcelo Sobarzo Sanchez



[1]     Mitchell Bacho, Eduardo Coelho-Cerqueira, Cristian Follmer, Seyed Mohammad Nabavi, Luca Rastrelli, Eugenio Uriarte, Eduardo Sobarzo-Sánchez. A medical approach to the monoamine oxidase inhibition by using 7H-benzo[e]perimidin-7-one derivatives. Curr. Top. Med. Chem., 2016, in press


[2]     Rosario Randino, Ilaria Moronese, Elena Cini, Valentina Bizzarro, Marco Persico, Manuela Grimaldi, Mario Scrima, Anna Maria D’Ursi, Ettore Novellino, Eduardo Sobarzo-Sánchez, Luca Rastrelli, Caterina Fattorusso, Antonello Petrella, Manuela Rodriquez and Maurizio Taddei. Benzodiazepine scaffold as drug-like molecular simplification of FR235222: a chemical tool for exploring HDAC inhibition. Curr. Top. Med. Chem., 2016, in press


[3]     Seyed Fazel Nabavi, Antoni Sureda, Maria Daglia, Morteza Izadi, Eduardo Sobarzo-Sánchez, Luca Rastrelli, Seyed Mohammad Nabavi. Flavonoids and Chagas’ disease: the story so far!. Curr. Top. Med. Chem., 2016, in press


[4]     Seyed Fazel Nabavi, Solomon Habtemariam, Maria Daglia, Antoni Sureda, Eduardo Sobarzo-Sánchez, Zeliha Selamoglu, Mehmet Fuat Gulhan, Seyed Mohammad Nabavi. Melatonin and respiratory diseases: a review. Curr. Top. Med. Chem., 2016, in press


[5]     Aouatef  Tabbi, Dahmane Tebbani, Angelamaria Caporale, Carmela Saturnino, Seyed Mohammad Nabavi, Palma Giuseppe, Claudio Arra, Zerrin Cantürk, Gülhan Turan-Zitouni, Hocine Merazig, Eduardo Sobarzo-Sánchez, Luca Rastrelli. New adamantyl chalcones: Synthesis, antimicrobial and anticancer activities. Curr. Top. Med. Chem., 2016, in press


[6]     Javed Sana; Tariq Ameema; Ahmed Touqeer; Budzynska Barbara; Tejada Silvia; Daglia Maria; Nabavi Seyed Fazel; Sobarzo-Sanchez Eduardo; Nabavi Seyed Mohammad. Tanshinones and mental diseases: from chemistry to medicine. Rev. Neuroscience, 2016. in press.


[7]     Seyed Fazel Nabavi, Eugenio Uriarte, Luca Rastrelli, Brenda Modak and Eduardo Sobarzo-Sánchez. Aporphines and Parkinson’s Disease: Medical Tools for the Future. Curr. Top. Med. Chem., 2016, 16(17), 1906-1909.


[8]     Anna Capasso, Eduardo Sobarzo-Sánchez, Seyed Fazel Nabavi and Luca Rastrelli. Cannabinoids for the Treatment of Schizophrenia: An Overview. Curr. Top. Med. Chem., 201616(17), 1916-1923.


[9]     Touqeer Ahmed, William N. Setzer, Seyed Fazel Nabavi, Ilkay Erdogan Orhan, Nady Braidy, Eduardo Sobarzo-Sanchez and Seyed Mohammad Nabavi. Insights into Effects of Ellagic Acid on the Nervous System: A Mini Review. Curr. Pharm. Des.201622, 1350-1360.


[10] Seyed Fazel Nabavi, Alistair J. Barber, Carmela Spagnuolo, Gian Luigi Russo, Maria Daglia, Seyed Mohammad Nabavi, and Eduardo Sobarzo-Sánchez. Nrf2 as molecular target for polyphenols: A novel therapeutic strategy in diabetic retinopathy. Crit. Rev. Clin. Lab. Sci., 201653(5), 293-312.


[11] Seyed Fazel Nabavi, Raman Thiagarajan, Luca Rastrelli, Maria Daglia, Eduardo Sobarzo-Sánchez, Heshmatollah Alinezhad and Seyed Mohammad Nabavi. Curcumin: A Natural Product for Diabetes and its Complications. Curr. Top. Med. Chem., 201515(23), 2445-2455.


[12] Seyed Fazel Nabavi, Nady Braidy, Olga Gortzi, Eduardo Sobarzo-Sanchez, Maria Daglia, Krystyna Skalicka-Wozniak, Seyed Mohammad Nabavi. Luteolin as an anti-inflammatory and neuroprotective agent: A brief review. Brain Res. Bull., 2015119, 1-15.


[13] Seyed Fazel Nabavi, Arianna Di Lorenzo, Morteza Izadi, Eduardo Sobarzo-Sánchez, Maria Daglia and Seyed Mohammad Nabavi. Antibacterial Effects of Cinnamon: From Farm to Food, Cosmetic and Pharmaceutical Industries. Nutrients, 20157, 7729-7748.


[14] Seyed Fazel Nabavi, Solomon Habtemariam, Touqeer Ahmed, Antoni Sureda, Maria Daglia, Eduardo Sobarzo-Sánchez and Seyed Mohammad Nabavi. Polyphenolic Composition of Crataegus monogyna Jacq.: From Chemistry to Medical Applications. Nutrients, 20157, 7708-7728.


[15] Nuñez, Jorge; Fontenla, Jose A.; Nabavi, Seyed Mohammad; Uriarte, Eugenio; Herrera, Alejandra; Sobarzo-Sanchez, Eduardo. Anxiolytic-Like Effects of 7H-Benzo[e]perimidin-7-One Derivatives through Elevated Plus-Maze Test in Mice. Curr. Top. Med. Chem., 201515(17), 1750-1754.
[16] Eduardo Sobarzo-Sánchez. Editorial (Thematic Issue: "Heterocycle and Hydrocarbon Compounds from Natural Sources in Medicinal Chemistry: From Synthesis to Computational Design in Pharmacological Applications" - Part 1). Curr. Top. Med. Chem., 201515(17), 1641-1642.


[17] Seyed Fazel Nabavi, Maria Daglia, Rosa Tundis, Monica Rosa Loizzo, Eduardo Sobarzo-Sánchez, Ilkay Erdogan Orhan, Seyed Mohammad Nabavi. Genistein: a Boon for Mitigating Ischemic Stroke. Curr. Top. Med. Chem., 201515(17), 1714-1721.
[18] Eduardo Sobarzo-Sánchez, Seyed Mohammad Nabavi, Eugenio Uriarte, Lourdes Santana. Nanoparticles in the Treatment of Mental Disorders: A New Tool in the Psychiatric Medication. Curr. Top. Med. Chem., 201515, 282-286.


[19] I.E. Orhan, M. Daglia, S.F. Nabavi, M.R. Loizzo, E. Sobarzo-Sánchez, S.M. Nabavi. Flavonoids and Dementia: An Update. Curr. Med. Chem., 201522, 1004-1015.


[20] Seyed F. Nabavi, Maria Daglia, Giuseppe D’A ntona, Eduardo Sobarzo-Sánchez, Zeliha S. Talas, Seyed M. Nabavi. Natural Compounds Used as Therapies Targeting to Amyotrophic Lateral Sclerosis. Curr. Pharm. Biotechnol., 201516, 211-218.


[21] Asteria Luzardo-Alvarez, Eduardo Sobarzo-Sánchez, José Blanco-Méndez, Francisco J. Otero-Espinar. Cyclodextrin-Based Polysaccharidic Polymers: An Approach for the Drug Delivery. Curr. Top. Med. Chem., 201414, 542-551.


[22] Leonardo Fernandes Fraceto, Renato Grillo, Eduardo Sobarzo-Sánchez. Cyclodextrin Inclusion Complexes Loaded in Particles as Drug Carrier Systems. Curr. Top. Med. Chem., 201414, 518-525.


[23] Miriam Cebey López, José A. Fontenla, Eugenio Uriarte, Lourdes Santana, Eduardo Sobarzo-Sánchez. Comparison of the Antidepressive Effects of Trans-Resveratrol and 5-Methoxy-7H-Dibenzo[de,h]Quinolin-7-One. Curr. Top. Med. Chem., 201414, 234-238.


[24] Akbar Hajizadeh Moghaddam, Eduardo Sobarzo-Sánchez, Seyed Fazel Nabavi, Maria Daglia, Seyed Mohammad Nabavi. Evaluation of the Antipsychotic Effects of 2-(dimethylamino)- and 2-(methylamino)-7H-naphtho[1,2,3-de]quinolin-7-one Derivatives in Experimental Model of Psychosis in Mice. Curr. Top. Med. Chem., 201414, 229-233.
[25] Eduardo Sobarzo-Sánchez. Editorial (Thematic Issue: “Alkaloids in Nature: Synthesis, Isolation and Pharmacological Applications” Part 2). Curr. Top. Med. Chem., 201414, 189-190.


[26] Seyed Fazel Nabavi, Eduardo Sobarzo-Sánchez, Seyed Mohammad Nabavi, Maria Daglia, Akbar Hajizadeh Moghaddam, Andrea García Silva. Behavioral Effects of 2,3-Dihydro- and Oxoisoaporphine Derivatives in Post Stroke-Depressive Like Behavior in Male Balb/c Mice. Curr. Top. Med. Chem., 201313, 2127-2133.
[27] Eduardo Sobarzo-Sánchez. Editorial (Thematic Issue: “ Alkaloids in Nature: Synthesis, Isolation and Pharmacological Applications” Part 1). Curr. Top. Med. Chem., 201313, 2097-2098.
[28] Eduardo Sobarzo-Sánchez, Pablo Bilbao-Ramos, Maria Dea-Ayuela, Humberto González-Díaz, Matilde Yañez, Eugenio Uriarte, Lourdes Santana, Victoria Martínez-Sernández, Francisco Bolás-Fernández, Florencio M. Ubeira. Synthetic Oxoisoaporphine Alkaloids: In Vitro, In Vivo and In Silico Assessment of Antileishmanial Activities. Plos One. 20138, e77560.


[29] Seyed Fazel Nabavi, Eduardo Sobarzo-Sánchez, Seyed Mohammad Nabavi, Antoni Sureda, Akbar Hajizadeh Moghaddam. Bi-3-Azaoxoisoaporphine Derivatives have Antidepressive Properties in a Murine Model of Post Stroke-Depressive Like Behavior. Curr. Neurovasc. Res., 201310, 164-171.


[30] Fernanda Pérez-Cruz, Benjamín Aguilera-Venegas, Michel Lapier, Eduardo Sobarzo-Sánchez, Eugenio Uriarte Villares, Claudio Olea-Azar. Host-guest interaction between new nitrooxoisoaporphine and b-cyclodextrins: Synthesis, Electrochemical, Electron spin resonance and Molecular modelling studies. Spectrochim. Acta Mol. Biomol. Spectros., 2013102, 226-234.
[31] Eduardo Sobarzo-Sánchez, Patricio González Soto, Cristóbal Valdés Rivera, Georgina Sánchez, María Eliana Hidalgo. Applied Biological and Physicochemical Activity of Isoquinoline Alkaloids: Oxoisoaporphine and Boldine. Molecules.201217, 10958-10970.


[32] E. Molina, E. Sobarzo-Sánchez, A. Speck-Planche, M.J. Matos, E. Uriarte, L. Santana, M. Yañez, F. Orallo. Monoamino Oxidase A: an interesting pharmacological target for the development of multi-target QSAR. Mini-Rev. Med. Chem., 201212, 947-958.


[33] Luis Nogueiras-Nieto, Eduardo Sobarzo-Sánchez, José Luis Gómez-Amoza, Francisco J. Otero-Espinar. Competitive displacement of drugs from cyclodextrin inclusion complex by soluble polypseudorotaxane formation with poloxamer: implications in drug solubilization and delivery. Eur. J. Pharm. Biopharm., 201280, 585-595.


[34] Francisco Prado-Prado, Xerardo García-Mera, Manuel Escobar, Eduardo Sobarzo-Sánchez, Matilde Yañez, Florencio M. Ubeira, Laura Muiño Pose, Pablo Riera-Fernandez, Humberto González-Díaz. 2D MI-DRAGON: a new predictor for protein-ligands interactions and theoretic-experimental studies of US FDA drug-target network, oxoisoaporphine inhibitors for MAO-A and Human parasite proteins. Eur. J. Med. Chem., 201146, 5838-5851.


[35] Christian Aliaga, Masiel Cerón-Neculpán, Claudio Saitz, Carolina Jullian, Eduardo Sobarzo-Sánchez, Julio R. De la Fuente. Oxoisoaporphines: Regioselective deuterium labelling involving the metastable hydrogenated photoproduct anions.J. Photochem. Photobiol.A: Chemistry. 2011222, 360-365.


[36] Christian Folch-Cano, Claudio Olea-Azar, Eduardo Sobarzo-Sánchez, Carmen Alvarez-Lorenzo, Angel Concheiro, Francisco Otero E., Carolina Jullian. Inclusion complex of 4-hydroxycoumarin with cyclodextrins and its characterization in aqueous solution. J. Solution Chem.. 201140, 1835-1846.


[37] Humberto González-Díaz, Francisco Prado-Prado, Eduardo Sobarzo-Sánchez, Mohamed Haddad, Séverine Maurel Chevalley, Alexis Valentin, Joëlle Quetin-Leclercq, María A. Dea-Ayuela, María Teresa Gomez-Muños, Cristian R. Munteanu, Juan José Torres-Labandeira, Xerardo García-Mera, Ricardo A. Tapia, Florencio M. Ubeira. NL MIND-BEST: a web server for ligands & proteins discovery; theoretic-experimental study of proteins of Giardia lamblia and new compounds active against Plasmodium falciparum. J. Theor. Biol., 2011276, 229-249.
[38] Sobarzo-Sanchez, Eduardo; Uriarte, Eugenio; Santana, Lourdes; Tapia, Ricardo A.; Perez Lourido, Paulo. New Approaches to 6-Oxoisoaporphine and Tetrahydroisoquinoline Derivatives. Helv. Chim. Acta. 201093, 1385-1394.


[39] María E Hidalgo; Myriam G. Alarcón; Juan R. Ojeda; Ernesto C. Fernández; Eduardo M. Sobarzo-Sánchez; Julio R. De la Fuente. Spectroscopic and Photochemical Properties of some Annelated Boldine Derivatives. J. Braz. Chem. Soc., 201021, 2205-2210.


[40] De la Fuente, Julio R.; Aliaga, Christian; Poblete, Cristian; Zapata, Gerald; Jullian, Carolina; Saitz, Claudio; Canete, Alvaro; Kciuk, Gabriel; Sobarzo-Sanchez, Eduardo; Bobrowski, Krzysztof. Photoreduction of Oxoisoaporphines by Amines: Laser Flash and Steady-State Photolysis, Pulse Radiolysis, and TD-DFT Studies. J. Phys. Chem. A. 2009113, 7737-7747.


[41] Julio De la Fuente, Gabriel Kciuk, K. Bobrowski, Eduardo Sobarzo-Sánchez. Transient phenomena in the pulse radiolysis of oxoisoaporphine derivatives in acetonitrile. J. Phys. Chem. A. 2008112, 10168-10177.


[42] Giovanni Valitutti, Eduardo Sobarzo-Sánchez, Pietro Traldi. The behaviour of M+. and [M+H]+ ions of some oxoisoaporphines and isoquinoline analogs. Heterocycles. 200875, 2213-2223.


[43] Eduardo Sobarzo-Sánchez, Luis Castedo,  Julio R. De la Fuente. Synthesis of anabaseine and anabasine derivatives: Structural modifications of possible nicotinic agonists. Synth. Commun., 200737, 1331-1338.


[44] Eduardo Sobarzo-Sánchez, Julio De la Fuente, Elías Quezada, Luis Castedo. Complete assignments 1H and 13C NMR spectral data of four anabaseine derivatives. Magn. Reson. Chem., 200644, 1131-1134.


[45] Eduardo Sobarzo-Sánchez, Luis Castedo, Julio R. De la Fuente. Synthesis and Theoretical Study on 5,6-Dimethoxy-2,3-Dihydro-7H-Dibenzo[de,h]Quinolin-7-one: Possible Precursor on the Aromatic Demethoxylation in Oxoisoaporphines.Struct. Chem., 200617, 483-489.
[46] Eduardo Sobarzo-Sánchez, Julio De la Fuente, Luis Castedo. Synthesis and total assignment of 1H and 13C NMR spectra of new oxoisoaporphines by long-range heteronuclear correlations. Magn. Reson. Chem., 200543, 1080-1083.


[47] Dolores M. Ivorra, Miguel Valiente, Sonia Martinez, Yolanda Madrero, Antonia M. Noguera, Bruce K. Cassels, Eduardo M. Sobarzo, Pilar D'Ocon. 8-NH2-boldine, an antagonist of a1A and a1B adrenoceptors without affinity for the a1Dsubtype: Structural requirements for aporphines at a1-adrenoceptor subtypes. Planta Med., 200571, 897-903.


[48] Julio R. De la Fuente, Verónica Neira, Claudio Saitz, Carolina Jullian, Eduardo Sobarzo-Sánchez. Photoreduction of oxoisoaporphines dyes by amines: Transient-absorption and semiempirical quantum-chemical studies. J. Phys. Chem. A.2005109, 5897-5904.


[49] Julio R. De la Fuente, Carolina Jullian M., Claudio Saitz B., Verónica Neira P., Oscar Poblete, Eduardo Sobarzo-Sánchez. Unexpected Formation of 1-Diethylaminobutadiene in Photosensitized Oxidation of Triethylamine Induced by 2,3-Dihydro-oxoisoaporphine Dyes. A 1H NMR and Isotopic Exchange Study. J. Org. Chem., 200570, 8712-8716.


[50] Rebeca García-Fandiño, Eva M. Codesido, Eduardo Sobarzo-Sánchez, Luis Castedo, Juan R. Granja. Tamden RCM of dienynes for the construction of taxol-type carbocyclic systems. Org. Lett., 20046, 193-196.


[51] Julio R. De la Fuente, Carolina Jullian M., Claudio Saitz B., Eduardo Sobarzo-Sánchez, Verónica Neira, Claudio González, Rodrigo López, Hernán Pessoa-Mahana.. Photoreduction of oxoisoaporphines. Another example of a formal hydride-transfer mechanism. Photochem. Photobiol. Sci., 20043, 194-199.


[52] Eduardo Sobarzo-Sánchez, Claudio Olea-Azar, Jaime Alarcón, Lucía Opazo, Bruce K. Cassels. Cathodic Behavior of 2,3-dihydrooxoisoaporphines. J. Chil. Chem. Soc., 200348, 79-83.
[53] Eduardo Sobarzo-Sánchez, Bruce K. Cassels, Luis Castedo. Complete 1H and 13C NMR spectral assignment of hydrogenated oxoisoaporphine derivatives. Magn. Reson. Chem., 200341, 545-548.
[54] Eduardo Sobarzo-Sánchez, Bruce K. Cassels, Luis Castedo. An Expedient Synthesis of Unusual Oxoisoaporphine and Annelated Quinoline Derivatives. Synlett., 200311, 1647-1650.
[55] Eduardo Sobarzo-Sánchez, Bruce K. Cassels, Carolina Jullian, Luis Castedo.Complete Structural and Spectral Assignment of Oxoisoaporphines by HMQC and HMBC Experiments. Magn. Reson. Chem., 200341, 296-300.
[56] Eduardo Sobarzo-Sánchez, Bruce K. Cassels, Luis Castedo, Laura Valencia-Matarranz. Crystal structure of 5-methoxy-6-hydroxy-2,3-dihydro-7H-dibenzo[de,h]quinolin-7-one. Zeitschrift für Kristallographie NCS. 2003218, 77-78.
[57] Eduardo Sobarzo-Sánchez, Bruce K. Cassels, Luis Castedo, Laura Valencia-Matarranz, Paulo Pérez-Lourido. Crystal structure of 2,3,8,9,10,11-hexahydro-7H-dibenzo[de,h]quinolin-7-one. Zeitschrift für Kristallographie NCS. 2003218, 177-178.
[58] Eduardo Sobarzo-Sánchez, Bruce K. Cassels, Luis Castedo, Laura Valencia-Matarranz. Crystal structure of 2-[(3,4-dimethoxy)-phenethyl-3-(3,4-dimethoxy)-phenethyamino]-2,3-dihydro-isoindol-1-one. Zeitschrift für Kristallographie NCS.2003218, 79-80.
[59] Eduardo Sobarzo-Sánchez, Bruce K. Cassels, Luis Castedo, Laura Valencia-Matarranz. Crystal structure of 3-[(3-Oxo-1,3-dihydro-isobenzofuran-1-yl)-phenethyl-amino]-2-phenethyl-2,3-dihydro-isoindol-1-one. Zeitschrift für Kristallographie NCS. 2003218, 81-82.
[60] Eduardo Sobarzo-Sánchez, Bruce K. Cassels, Luis Castedo, Laura Valencia-Matarranz.Crystal structure of 5-methoxy-2,3-dihydro-7H-dibenzo[de,h]quinolin-7-one. Zeitschrift für Kristallographie NCS. 2003218, 83-84.


[61] Juan S. Gómez-Jeria, Eduardo Sobarzo-Sánchez. Theoretical study of the opioid receptor selectivity of some 7-arylidenenaltrexones. J. Chil. Chem. Soc., 200348, 61-66.
[62] Eduardo Sobarzo-Sánchez, Carolina Jullian, Bruce K. Cassels, Claudio Saitz. New Heterocyclic Skeletons Derived from the Aporphine Alkaloid Boldine. Synth. Commun., 200232, 3687-3693.


[63] Eduardo Sobarzo-Sánchez, Juan S. Gómez-Jeria. Estudio Teórico de la Regioselectividad de la Boldina en Reacciones de Sustitución Aromática. Bol. Soc. Chil. Quím., 200247, 477-484.
[64] Eduardo Sobarzo-Sánchez, Carolina Jullian, Bruce K. Cassels, Claudio Saitz.Oxazine- and oxazole- fused derivatives of the alkaloid boldine and their complete structural and spectral assignment by HMQC and HMBC experiments.Magn. Reson. Chem., 200139, 361-366.
[65] Eduardo M. Sobarzo-Sánchez, Jeannette Arbaoui, Philippe Protais, Bruce Cassels. Halogenated boldine derivatives with enhanced Monoamine receptor selectivity. J. Nat. Prod., 200063, 480-484.
[66] Eduardo Sobarzo-Sánchez, Juan S. Gómez-Jeria. Estudio teórico de la semiconductividad de algunos  aductos Diels-Alder del C60Bol. Soc. Chil. Quím., 199944, 191-197.


[67] S. Martínez, Y. Madrero, M. Elorriaga, M.-A. Noguera, B.K. Cassels, E. Sobarzo, P. D’Ocon, M.D. Ivorra. Halogenated derivatives of boldine with high selectivity for α1A-adrenoceptors in rat cerebral cortex. Life Sci., 199964, 1205-1214.