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Páxinas persoais  »  Antonio Mouriño Mosquera

Synthesized Vitamin D Analogues

THE MOURIÑO GROUP

 

  

The Mouriño group is engaged in the synthesis of vitamin D analogues of potential clinical interest employing new strategies for the construction of the triene unit, CD fragment and side chain. Of particular interest is the development of a flexible route to the total synthesis of the natural hormone 1,25D that would allow the synthesis of novel analogues which are difficult to prepare by the current synthetic routes. A selection of vitamin D analogues and metabolites synthesized in this laboratory are shown below.

 
SYNTHESIZED ANALOGUES-1  

 

SYNTHESIZED ANALOGUES-2

 

SYNTHESIZED ANALOGUES-3

 

SYNTHESIZED ANALOGUES-4